ABCD1

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ABCD1

A gene on chromosome Xp28, which encodes a member of the superfamily of ATP-binding cassette (ABC) transporters, which transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies—ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White. The ABCD1 protein product belongs to the ALD subfamily and is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in peroxisomes.

Molecular pathology
ABCD1 mutations are linked to adernoleukodystrophy.
References in periodicals archive ?
The advancement of ALDP alumni has been remarkable.
In addition, the ALDP will undergo regular reviews to maintain relevance.
Research contained in this handbook will provide the basis for expanded classroom training for ALDP mentors.
The success and popularity of the ALDP also provided the DOC with serendipitous benefits revealed long after predictable advantages were realized.
The ALDP emerged from a desire and need to elevate proficiency and improve internal potential for promotion.
Do you think ALDP helped you to become a better leader?
I would add the mentorship that occurred during ALDP proved to be beneficial beyond the tenure of the program.
What should be changed about ALDP for the next course?
The Selection Committee has learned that employees not selected for ALDP can become disenfranchised.
There are some data to suggest that people who complete ALDP are more likely to be promoted.
In fact, participants want the program to continue, so MNDOC is planning for annual ALDP get-together.