Detection of the transforming AKT1
mutation E17K in non-small cell lung cancer by high resolution melting.
, ERK1/2, p38 MAPK, and NF-[kappa][beta]), resulting in cellular apoptosis.
, AKT2, E2F1, IKK and NF-[kappa]B1) exhibited down-regulation.
A potassium channel, OsAKT1, homologous to the Arabidopsis root inward rectifier AKT1
Association of polymorphisms in AKT1
and EGFR with clinical outcome and toxicity in non-small cell lung cancer patients treated with gefitinib.
In EAT, there were increases in the insulin receptor ( IR) and IR substrate 2 ( IRS2) mRNA, but CE-induced increases in mRNA expression of IRS1, phosphoinositide-3-kinase, AKT1
, glucose transporters 1 and 4, and glycogen synthase 1 expression and decreased trends in mRNA expression of glycogen synthase kinase 3beta were not statistically significant.
Genetic inactivation of AKT1
, AKT2, and PDPK1 in human colorectal cancer cells clarifies their roles in tumor growth regulation.
A eles, podem-se acrescentar os resultados de um prestigioso estudo multicentrico europeu de 2008, que testou a relacao entre esquizofrenia e catorze dos principais nucleotideos unicos associados pela literatura (RGS4, DISC1, DTNBP1, STX7, TAAR6, PPP3CC, NRG1, DRD2, HTR2A, DAOA, AKT1
, CHRNA7, COMT e ARVCF), nao encontrando relacao significativa para nenhum deles, o que per se relativiza a atratividade de Hipoteses Etiologicas Unificadas em geral (Sanders, et al.
Molecular cloning of the akt oncogene and its human homologues AKT1
and AKT2:amplification of AKT1
in a primary human gastric adenocarcinoma.
Within the AKT cascade, the response variable consisted of eight correlated gene expression values for each placenta--that is, two biopsies per placenta and four target genes (BDNF, AKT1
, AKT2, and AKT3) measured in each biopsy.
Combined effects of genetic variants of the PTEN, AKT1
, MDM2 and p53 genes on the risk of nasopharyngeal carcinoma.
6] Human genes: EGFR, epidermal growth factor receptor; KRAS, Kirsten rat sarcoma viral oncogene homolog; TP53, tumor protein p53; NF2, neurofibromin 2 (merlin); AKT1
, v-akt murine thymoma viral oncogene homolog 1; BRAF, B-Raf proto-oncogene, serine/ threonine kinase; NRAS, neuroblastoma RAS viral (v-ras) oncogene homolog; KMT2D, lysine (K)-specific methyltransferase 2D; NSD1, nuclear receptor binding SET domain protein 1; CREB3L1, cAMP responsive element binding protein 3-like 1; TPR, translocated promoter region, nuclear basket protein; TSC2, tuberous sclerosis 2.