AKAP4

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AKAP4

A gene on chromosome Xp11.2 that encodes a member of the structurally diverse A-kinase anchor protein (AKAP) family, which binds to the regulatory subunit of protein kinase A, confining the enzyme to discrete locations within the cell. AKAP4 localises to sperm flagella and may be involved in regulating sperm motility.
References in periodicals archive ?
first reported the aberrant expression of the cancer-testis antigen A-kinase anchor protein-4 (AKAP-4) in prostate cancer, which will potentially be developed as a biomarker in prostate cancer.
Mirandola et al., "Identification of AKAP-4 as a new cancer/testis antigen for detection and immunotherapy of prostate cancer," The Prostate, vol.