AIP


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AIP

(1) A 330 residue protein that helps stabilise the AIP-hsp90-AhR complex and protects the AhR receptor from ubiquitination under heat-stress conditions; AIP may also play a role in regulating the rate of AhR turnover by delaying AhR nuclear translocation after ligand binding.
(2) A gene on chromosome 11q13.3 that encodes a receptor for aryl hydrocarbons and a ligand-activated transcription factor. It resides in the cytoplasm as part of a multiprotein complex and is transported to the nucleus once it binds with a ligand. AIP regulates the expression of many xenobiotic metabolising enzymes; it binds specifically to and inhibits the activity of hepatitis B virus.

AIP

Acute intermittent porphyria
References in periodicals archive ?
reported that abundant infiltration of TLR-7 positive M2 macrophages was observed in the pancreatic tissues in type 1 AIP patients [35].
The (AIP) is disappointed (in the government) for not addressing these cases, he said, adding that even the Freedom of Information (FOI) bill has not seen the light of day under the Aquino administration.
13, 2012, the first step of negotiations was taken with the release of a Preliminary Draft Agreement-in-Principle (AIP) for public review.
Participants in the AIP care coordination program demonstrated significantly better clinical and cost outcomes when compared to similar individuals in nursing homes and HCBS.
In contrast, no such variations are seen in healthy Chinese population (Figure-2), suggesting that this variation could play a role in AIP. Literature search and data from Gene Bank remained unrevealing, which makes this case the first to be reported.
AIP is the most common manifestation of IgG4-related disease, but extrapancreatic involvement is not uncommon, with up to 77% of cases having extrapancreatic involvement.
The overall prevalence of clinically manifest AIP is estimated to be 50-500/million.
According to the company, the results suggested the AAV5 vector from uniQure's bacculovirus production platform is safe by inducing liver cell transfection in AIP patients without liver enzyme perturbations at the tested dose levels.
AIP said the investment was made out of its USD717.5m American Industrial Partners Capital Fund V LP, which closed in December 2011.
Two major mechanisms attempt to explain the pancreatic stone formation observed in AIP: calcification after severe inflammation or tissue necrosis specific to AIP and stasis of pancreatic juice due to irregular narrowing of the pancreatic duct [13].
Founded in 1989, AIP manages more than $1.1 billion in capital.
As we open the 2013 AIP assignments season this month, I ask all of you to consider what you might do to support these key posts that are so critical to our country's national security.