AURKC

(redirected from AIK3)

AURKC

A gene on chromosome 19q13.43 that encodes Aurora kinase C, which is involved in regulating many mitotic events. Aurora C is the serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), which is critical for the correct progression through and completion of mitosis. It has redundant cellular functions with AURKB; both phosphorylate histone H3. AURKC also phosphorylates TACC1, another protein involved in cell division.
References in periodicals archive ?
The Aurora-C is encoded by the AURKC gene (also known as AIE2; AIK3; ARK3; AurC; SPGF5; STK13), which localizes at chromosome 19q13.43 and consists of 7 exons (Gene ID: 6795).
Okano, "Cell cycle-dependent expression and centrosome localization of a third human Aurora/Ipl1-related protein kinase, AIK3," The Journal of Biological Chemistry, vol.