FGF8

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FGF8

A gene on chromosome 10q24 that encodes fibroblast growth factor 8 of the FGF family, which bind heparin and have a broad range of cellular activities, including cell survival, division, differentiation and migration, embryonic development, morphogenesis, tissue repair, tumour growth and invasion. FGF8 is expressed in adults only in the testes and ovaries; it is required for normal brain, eye, ear and limb development during embryogenesis, and for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. FGF8 interacts with FGF receptors FGFR1, -2, -3 and -4.

Molecular pathology
Defects in FGF8 cause Kallmann syndrome type 6.
References in periodicals archive ?
AIGF will be the core platform in Southeast Asia for MC s private equity business which comprises of a diversified mix of investment strategies that span emerging and developed markets, with investment focus from small caps to large corporations.
Despite such criticisms, the AIGF distributed A$10 million in 2012/13 and 2013/14 to studios, individual games projects, and sector-building initiatives.
Screen Australia's most visible approach to distributing the AIGF was a scattergun strategy of allocating small amounts of money to many projects in the hope that a handful might become a success.
AIGF is a unique platform that seeks to match the growing interest of Japanese corporates for ASEAN business opportunities to the strong demand for Japanese expertise among ASEAN corporations.
These factors are the key drivers of our investment thesis for AIGF.