FGF8

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FGF8

A gene on chromosome 10q24 that encodes fibroblast growth factor 8 of the FGF family, which bind heparin and have a broad range of cellular activities, including cell survival, division, differentiation and migration, embryonic development, morphogenesis, tissue repair, tumour growth and invasion. FGF8 is expressed in adults only in the testes and ovaries; it is required for normal brain, eye, ear and limb development during embryogenesis, and for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. FGF8 interacts with FGF receptors FGFR1, -2, -3 and -4.

Molecular pathology
Defects in FGF8 cause Kallmann syndrome type 6.
References in periodicals archive ?
The AIGF, in its white paper submitted to the Law Commission of India (LCI), stated the Centre could earn thousands of crores in tax and revenues every year if it legalises betting.
The remainder of the money was split between individual games (through the AIGF's production arm) and sector-building initiatives (full disclosure: the festival that I currently direct, the Freeplay Independent Games Festival, received A$20,000 via this arm of the fund, though this predates my time in the position).
Ultimately, thirty-six games were funded by the AIGF's Games Production arm, and most are still unreleased.
The upshot, however, is that the cancellation of the AIGF returns us to the status quo, whereby the federal government continues to exercise and finesse its ability to regulate and censor video games, but with no means
AIGF will be the core platform in Southeast Asia for MC s private equity business which comprises of a diversified mix of investment strategies that span emerging and developed markets, with investment focus from small caps to large corporations.
AIGF is a unique platform that seeks to match the growing interest of Japanese corporates for ASEAN business opportunities to the strong demand for Japanese expertise among ASEAN corporations.
These factors are the key drivers of our investment thesis for AIGF.
AIGF will focus on well established companies and will seek to generate returns by working closely with management teams as well as playing an active role in assisting them to reach their full potential, both locally and regionally.
MIGA and the AIGF are currently covering a total of $76.5 million under the project.