A gene on chromosome 22q11.21 that encodes a protein which induces apoptosis through a caspase-dependent pathway by reducing mitochondrial membrane potential.
MiR-210 also promotes cardiac cell survival by blocking expression of the negative regulators of VEGF signaling (Efna3 and Ptp1b) and apoptosis inducing factor-mitochondrion associated 3 (AIFM3) [81, 82].