ACTG

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ACTG

AIDS Clinical Trials Group. An HIV/AIDS clinical trials organisation established in 1987 to broaden the scope of the AIDS research effort of the US National Institute of Allergy and Infectious Diseases (NIAID). The ACTG supports the largest network of expert clinical and translational investigators and therapeutic clinical trials units in the world, including sites in resource-limited countries, whose investigators and units serve as the major resource for HIV/AIDS research, treatment, care, and training/education in their communities. It has been pivotal in providing the data necessary for approval of therapeutic agents, as well as the treatment and prevention strategies for many opportunistic infections and malignancies. The ACTG is composed of, and directed by, leading clinical scientists in HIV/AIDS therapeutic research and funded by the US Department of Health and Human Services, NIH through the NIAID.

ACTG

Abbrev for . AIDS Clinical Trials Group. This is a large US government-sponsored organisation dedicated to research into the treatment of AIDS.
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AIDS-related Kaposi's sarcoma: Prospective validation of the AIDS Clinical Trials Group staging classification.
(6.) Sterling TR, Scott NA, Miro JM, et al.; Tuberculosis Trials Consortium; AIDS Clinical Trials Group for the PREVENT TB Trial.
(ACTG, AIDS Clinical Trials Group; SHCS, Swiss HIV Cohort Study; images from Servier PowerPoint Image Bank http://www.servier.com/Powerpoint-image-bank.) Impact of poor adherence on mortality Model of HIV disease Improving adherence from 50% to progression (20) 80% adds up to 2 life-years Improving adherence from 80% to 100% adds up to 4.8 life-years 3ISO in SHCS starting ART Missing >2 doses in past 4 weeks 2003-2013 (18) raises death risk 2.89-fold IN MSM missing >2 doses in past 4 weeks raises death risk 4.87-fold 643 ACTG participants enrolled Time-updated nonadherence raises 1997-1999 (21) AIDS progression/death risk 1.84-fold
Where this therapy is not used for any reason, patients with visceral lesions, even asymptomatic, should be considered in accordance with the classification of ACTG (AIDS Clinical Trials Group Oncology Committee) and treatment should be optimized.
Comparison of once-daily versus twice-daily combination antiretroviral therapy in treatment-naive patients: results of AIDS clinical trials group (ACTG) A5073, a 48-week randomized controlled trial.
Tripathy, Scientist F, National AIDS Research Institute (NARI), Pune, participated in the Adult AIDS Clinical Trials Group Meeting at Washington, D.C.
Sharon Nachman on behalf of the Pediatric AIDS Clinical Trials Group 1055.
Some of the largest HIV clinical trials contribute so little to the development of knowledge that I have sarcastically suggested that the AIDS clinical trials group of the NIH should be moved to the Department of Highways.
In a study undertaken by the Pediatric AIDS Clinical Trials Group of the National Institute of Child Health and Human Development, 497 HIV-infected women were enrolled and levels of HIV RNA, CD4+ lymphocytes, and p24 antibodies were determined at baseline and delivery.
These guidelines were prepared by a team of clinical scientists on the Cardiovascular Subcommittee of the AIDS Clinical Trials Group (ACTG), who updated preliminary recommendations published in 2000.
Zidovudine, didanosine, or both as the initial treatment for symptomatic HIV-infected children: AIDS Clinical Trials Group (ACTG) Study 152 Team.

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