ACTG

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ACTG

AIDS Clinical Trials Group. An HIV/AIDS clinical trials organisation established in 1987 to broaden the scope of the AIDS research effort of the US National Institute of Allergy and Infectious Diseases (NIAID). The ACTG supports the largest network of expert clinical and translational investigators and therapeutic clinical trials units in the world, including sites in resource-limited countries, whose investigators and units serve as the major resource for HIV/AIDS research, treatment, care, and training/education in their communities. It has been pivotal in providing the data necessary for approval of therapeutic agents, as well as the treatment and prevention strategies for many opportunistic infections and malignancies. The ACTG is composed of, and directed by, leading clinical scientists in HIV/AIDS therapeutic research and funded by the US Department of Health and Human Services, NIH through the NIAID.

ACTG

Abbrev for . AIDS Clinical Trials Group. This is a large US government-sponsored organisation dedicated to research into the treatment of AIDS.
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Racial differences in response to antiretroviral therapy for HIV infection: An AIDS Clinical Trials Group (ACTG) study analysis.
Prolonged evaluation of protocol 019 of the AIDS Clinical Trials Group.
NIAID is currently assessing, in a study known as AIDS Clinical Trials Group (ACTG) 842, the prevalence of idiopathic genital ulcer disease in HIV-infected women and the effect of thalidomide treatment.
To get an up-to-date look at how HCV affects people with HIV infection, AIDS Clinical Trials Group researchers combined the results of four studies of antiretroviral therapy.
To assess the public health burden of coinfection in this population, he and his colleagues analyzed data from the National Institutes of Health--sponsored AIDS Clinical Trials Group (ACTG) Longitudinal Linked Randomized Trials cohort.
He also served as Community Constituency Representative to the American Foundation for AIDS Research (amfAR) and the AIDS Clinical Trials Group.
An AIDS Clinical Trials Group (ACTG) study found that Ziagen plus Epivir (lamivudine) did not stop HIV as well as Viread (tenofovir) plus Emtriva (emtric-itabine) when given with Sustiva (efavirenz) or Reyataz (atazanavir) to people starting their first antiretrovirals with a viral load over 100,000.
Swindells cautioned that her study--which was conducted under the auspices of the AIDS Clinical Trials Group (a clinical trials organization funded by the National Institutes of Health) and was supported by grants from the NIH, Bristol-Myers Squibb Co.
Riddler and her coinvestigators of the open-label, prospective AIDS Clinical Trials Group (ACTG) 5142 study compared these three regimens in 753 naive subjects with HIV RNA greater than 2,000 copies/mL and any CD4 cell count.
Before 1995, primarily the Adult AIDS Clinical Trials Group (AACTG) conducted multicenter AIDS-related cancer trials.
1) This finding from an AIDS Clinical Trials Group (ACTG) study underlines the danger of interrupting antiretrovirals--especially nonnucleosides--unless your doctor recommends and plans the interruption.

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