Alkhurma hemorrhagic fever

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Alkhurma hemorrhagic fever

Abbreviation: AHFV

A tick-borne hemorrhagic fever caused by a flavivirus, first identified on the Arabian peninsula.

See also: fever

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Wintering (light brown) and breeding (green) locations and springtime migratory routes (arrows) of birds testing positive for Alkhurma hemorrhagic fever virus (AHFV) RNA in Greece and Turkey, 2010 and 2014.

Nucleotide alignments of novel AHFV sequences obtained from Hyalomma marginatum sensu lato ticks (likely H.

Alkhurma Hemorrhagic Fever Virus RNA in Hyalomma rufipes Ticks Infesting Migratory Birds, Europe and Asia Minor

No nonsynonymous mutations were observed in the envelope gene of the 11 sequences determined for human AHFV cases or in tick and human AHFV sequences.

As shown in the Figure, the AHFV-JE7 sequence was closely related to but unambiguously distinct from all other AHFV sequences from human isolates.

Alkhurma hemorrhagic fever virus in Ornithodoros savignyi ticks

Sequences from the 11 AHFV isolates were compared with homologous sequences representing other tickborne flaviviruses retrieved from the GenBank database: Langat virus (LGTV) (M73835), Powassan virus (POWV) (L06436), deer tick virus (DTV) (AF311056), Omsk hemorrhagic fever virus (OHFV) (AY323489), Kyasanur Forest disease virus (KFDV) (AY323490 for envelope sequence, and personal data for NS3 and NS5 sequence), tick-borne encephalitis virus (TBEV) Neudoerfl strain (U27495), Hypr strain (U39392), Vasilchenko strain (L40361), Sofjin strain (AB062064), and Louping ill virus (LIV) (Y07863).

(8), which permitted the evaluation of divergence times among AHFV isolates and between AHFV and KFDV.

Low diversity of Alkhurma hemorrhagic fever virus, Saudi Arabia, 1994-1999

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