DAX1

(redirected from AHCH)
Also found in: Acronyms.

DAX1

A gene (DSS-AHC critical region on the X chromosome, gene 1—formally known, per HUGO nomenclature, as NR0B1) located on chromosome Xp21.3 that encodes a protein containing a DNA-binding domain, which acts as a dominant-negative regulator of transcription mediated by the retinoic acid receptor. DAX1 also acts as an anti-testis gene by antagonising SRY.

Molecular pathology
DAX1 mutations cause both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.
References in periodicals archive ?
He is so thankful to Alder Hey Children's Hospital in Liverpool for what they have done, he has even had a tattoo of the hospital logo and AHCH inked on his forearm.
En este sentido, el relato de AHCh, campesino oriundo de San Rafael de Escazu, en San Jose, muestra lo bajo que estaban los salarios en la Region Central, sobre todo en comparacion con aquellos que pagaban las bananeras del Caribe costarricense.
Aaron had requested in lieu of flowers please make donations to (PANCAN) Pancreatic Cancer Action Network 2141 Rosecrans Ave., Suite 7000, El Segundo, CA 90245 (www.pancan.org) to help eradicate this disease or to the Androscoggin Hospice House, 236 Stetson Rd., Auburn, ME 04210 (ahch.org)