AHR

(redirected from AH-receptor)

AHR

A gene on 7p15 that encodes aryl hydrocarbon receptor, a ligand-activated transcription factor involved in cell cycle regulation and in regulating biological responses to planar xenobiotic halogenated aromatic hydrocarbons.
References in periodicals archive ?
Bradfield, "The AH-receptor: genetics, structure and function," Pharmacogenetics, vol.
Bradfield, "Tissue specific expression of the rat Ah-receptor and ARNT mRNAs," Nucleic Acids Research, vol.
The model Ah-receptor agonist beta-naphthoflavone inhibits aflatoxin B-1-DNA binding in vivo in rainbow trout at dietary levels that do not induce CYP1A enzymes.
Work in a number of labs, including Bradfield's, suggests that the Ah-receptor protein traces evolutionarily to sensory systems in bacteria.
The Ah-receptor protein contains a region characterized by a pattern of repeating amino acids, called the PAS domain.
However, Safe's studies now indicate that when the Ah-receptor lock is keyless, it will link up with another protein, known as Arnt.
The most unexpected dividends of Ah-receptor understanding may emerge in medicine.
A human intervention study with foods containing natural Ah-receptor agonists does not significantly show AhR-mediated effects as measured in blood cells and urine.
Polybrominated diphenyl ethers (PBDEs) as Ah-receptor agonists and antagonists.