ANGPT1

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ANGPT1

A gene on chromosome 8q23.1 that encodes angiopoietin 1, a secreted glycoprotein which, like other angiopoietins, binds to endothelial cell-specific tyrosine-protein kinase receptor. It plays a key role in mediating interactions between the endothelium and surrounding matrix and mesenchyme, andit  inhibits endothelial permeability. Angiopoietin 1 plays a role in regulating angiogenesis; endothelial cell survival, proliferation, migration, adhesion and spreading; reorganisation of the actin cytoskeleton; and maintains vascular quiescence. It contributes to blood vessel maturation and stability and may be involved in cardiac embryogenesis.
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AGPT performed with serum from naturally infected birds and liver extracts as source of virus showed strong positive precipitation (results not shown).
The homogenate was centrifuged at 2000 rpm for 30 minutes and the supernatant was harvested and tested for viral antigen by the AGPT [12, 23].
Presence of second-generation virus was confirmed by AGPT test.
For example, the average diameter of the observed AgPt alloy NPs of AgPt-MWCNT-PET films was approximately 26 [+ or -] 8 nm after MW plasma treatment, which was much larger than that of the as-produced NPs (3.8 [+ or -] 0.65 nm), as shown in Figure 12.
Agar gel precipitation test: AGPT was used for the diagnosis of the causative agent as described by Beard (1978).
Agar gel precipitation test (AGPT) was found to be sensitive enough to detect trends in immune response / differences in antibody titer of three groups.
Indirect haemagglutination assay (IHA), enzyme enzyme linked immunosorbant assay (ELISA), agar gel precipitation test (AGPT), virus neutralization (VN) test, dot immunobinding assay (DIA) and immuno-electrophoresis using infected liver homogenate filtrate as crude antigen and specific antiserum have also been used in HPS diagnosis (Ganesh, 1998).