AGPAT1 | definition of AGPAT1 by Medical dictionary
AGPAT1 A gene on chromosome 6p21.3 that encodes an enzyme which localises to the endoplasmic reticulum, where it converts lysophosphatidic acid into phosphatidic acid, both of which are involved in signal transduction and lipid biosynthesis.
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References in periodicals archive
Stimulation of BMM was also associated with the upregulation of 1-acylglycerol-3-phosphate O-acyltransferase 1 (AGPAT1
) and phosphatidate cytidylyltransferase 1 (CDS1), which may increase cytidine diphosphate- (CDP-) diacylglycerol production, a precursor for phosphatidylinositol, phosphatidylglycerol, and cardiolipin synthesis.
2012), Huntington's disease (H2AFY2, AGPAT1
) (Cong et al.
The BMET array contains four genes of these isoforms, and AGPAT1
was the most abundant transcript in both tissues.