AFP


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alpha

 [al´fah]
the first letter of the Greek alphabet, α; used to denote the first position in a classification system; as, in names of chemical compounds, to distinguish the first in a series of isomers, or to indicate the position of substituent atoms or groups; also used to distinguish types of radioactive decay, brain waves or rhythms, adrenergic receptors, and secretory cells that stain with acid dyes, such as the alpha cells of the pancreas.
alpha-adrenergic blocking agent (alpha-blocker) (alpha-blocking agent) any of a group of drugs that selectively inhibit the activity of alpha receptors in the sympathetic nervous system. As with beta-adrenergic blocking agents, alpha-blocking agents compete with the catecholamines at peripheral autonomic receptor sites. This group includes ergot and its derivatives, and phentolamine.
alpha chain disease the most common heavy chain disease, occurring predominantly in young adults in the Mediterranean area, and characterized by plasma cell infiltration of the lamina propria of the small intestine resulting in malabsorption with diarrhea, abdominal pain, and weight loss, or, exceedingly rarely, by pulmonary involvement. The gastrointestinal form is immunoproliferative small intestine disease.
alpha-fetoprotein (AFP) a plasma protein produced by the fetal liver, yolk sac, and gastrointestinal tract and also by hepatocellular carcinoma, germ cell neoplasms, and other cancers in adults; elevated levels may also be seen in benign liver disease such as cirrhosis and viral hepatitis. The serum AFP level is used to monitor the effectiveness of cancer treatment.

During pregnancy some AFP crosses from the amniotic fluid to the mother's blood. If the fetus has a neural tube defect, large amounts of AFP will be found in the amniotic fluid and maternal blood. Blood screening tests for serum AFP can thus be done as a first step in the screening process; if test results are positive, further testing is indicated to diagnose the defect.
alpha particles a type of emission produced by the disintegration of a radioactive substance. The atoms of radioactive elements such as uranium and radium are very unstable, continuously breaking apart with explosive violence and emitting particulate and nonparticulate types of radiation. The alpha particles, consisting of two protons and two neutrons, have an electrical charge and form streams of tremendous energy when they are released from the disintegrating atoms. These streams of energy (alpha rays) can be used in treatment of various malignancies. See also radiation and radiation therapy.

AFP

Abbreviation for α-fetoproteins. See: fetoproteins.

AFP

abbr.
alpha-fetoprotein

AFP

A gene on chromosome 4q11-q13 that encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during foetal life. AFP is regarded as the foetal counterpart of serum albumin and binds copper, nickel, fatty acids and bilirubin; hereditary persistance of alpha-fetoprotein may be found in individuals with no obvious pathology.

Molecular pathology
AFP is elevated in foetuses with neural tube defects, including spina bifida and anencephaly. It is elevated in adults with hepatocellular carcinomas and germ cell tumours.

AFP

α-fetoprotein, see there.

AFP

Abbreviation for alpha(α) fetoprotein test.

AFP (Alpha-fetoprotein)

A tumor marker associated with liver, testicular, and ovarian cancer.
Mentioned in: Tumor Markers
References in periodicals archive ?
Major Key Features of Global Antifreeze Proteins (AFP) Market:
He also assured that the AFP will also continue to intensify its military operations, intelligence monitoring, community support programs and other efforts to prevent corrupt and destruction elements that intend to jeopardize and disrupt the conduct of the elections.
On the Serum AFP levels basis, they were separated into groups 1 (with serum levels lower than 20 IU/ml), 2 (serum from 20 to 399 IU/ml) and 3 with serum levels higher than 400 IU/ml.
Exogenous AFP can not only promote the proliferation of hepatocellular carcinoma cells and the formation of tumor blood vessels, but also enhance the antiapoptosis effect of cancer cells [14-18].
Notably, compared with the serum AFP < 20 ng/ml group, 10 (13.5%) patients were diagnosed with hepatoid adenocarcinoma in the AFP [greater than or equal to] 20 ng/ml group.
The results showed that AFP, AFP-L3, and ALT had relatively good predictive power for HCC progression; AUC were 0.736, 0.744, and 0.693, respectively (see Table 4, Figure 2).
Prince Faizuddin also met AFP Reserve Commander Col.
Very low AFP may indicate an increased risk of Down's syndrome.
Expresa que el sistema privado de pensiones "ha permitido que nuestros aportes generen una capitalizacion feroz en beneficio de los duenos de las AFP y se socialicen permanentemente las perdidas en detrimento de la gran mayoria de nuestro pueblo".
During 2015, seven cVDPV2s were isolated from patients aged <15 years with acute flaccid paralysis (AFP) in Kankan Province (up to 3% VP1 divergence).
(AFP Habitat), a leading provider of retirement services in Chile.