ADPKD
Also found in: Acronyms.
ADPKD
autosomal dominant polycystic kidney disease.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
autosomal dominant polycystic kidney disease
A common (1:400–1:1000) autosomal dominant condition (OMIM:173910), which causes 6–9% of end-stage renal disease in developed countries. ADPKD first appears in adults with upper quadrant tenderness; extrarenal disease is due to defective extracellular matrix, with hepatic cysts, diverticulosis, berry and abdominal aneurysms, annuloaortic ectasia and valvular regurgitation.Clinical findings
Acute or subacute onset of azotaemia and hypertension, due to increased activity of the renin-angiotensin-aldosterone (RAA) system, possibly related to the ischaemic pressure induced by the expanding cysts.
Lab
Anaemia, increased ESR, increased WBCs.
Diagnosis
Ultrasonography.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
ADPKD
Autosomal dominant polycystic kidney disease, see there.McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.