ADOPT


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ADOPT

Cardiology
Accupril Decision On PharmacoTherapy. A clinical trial that was planned at Vanderbilt University in Tennessee, the purpose of which was to compare efficacy and safety of quinapril, enalapril, atenolol and verapamil in controlling blood pressure in patients with uncomplicated mild to moderate hypertension when used as single-agent therapy in a structured titration program.
 
Endocrinology
A Diabetes Outcome Progression Trial. A 4-year Phase-4 trial comparing early treatment of type-2 diabetics with rosiglitazone (Avandia), metformin or glyburide (a sulfonylurea in glucose control) for delay or prevention of diabetes complications—e.g., kidney disease, etc.

Conclusion
Lower failure rate at 5 years: 15% with rosiglitazone vs. 21% with metformin and 34% with glyburide; a highly significant risk reduction of 32% for rosiglitazone compared with metformin, and 63% compared with glyburide. Positive results notwithstanding, rosiglitazone has been pulled from various markets due to possible increased risk of heart attacks.

ADOPT

Endocrinology A 4-yr phase IV trial–A Diabetes Outcome Progression Trial–comparing early treatment of Pts with type 2 DM with Avandia®, metformin, or glyburide–a sulfonylurea in glucose control, delay or prevention of DM complications–eg, kidney disease, etc
References in periodicals archive ?
He loves animals and started the non-profit organization, “Kids Adopt a Shelter,” to help animal shelters in December, 2011.
It is not clear to me that the European Commission will adopt a homogeneous approach to IAS 39, or whether they will endorse different versions for different regions," said Nagari.
In order for the Adopt a Teacher Program to honor and support more than two teachers each year, I need the support of our ACEI family and other professional colleagues.
Even so, many states allow gays to adopt as individuals and many--including California, Connecticut, the District of Columbia, Massachusetts, New Jersey, New York, and Vermont--now allow joint adoptions by same-sex couples.
107) Sophie Theis, the study's author and a major figure in adopt ion modernization, confessed that spotty early records hindered her inquiry.
The legislative history confirms that Congress intended to adopt the SEC's definitions of certain enumerated non-audit services, including the SEC's exceptions for appraisal, valuation, and actuarial tax services.
It adopted the Strasbourg Convention in November 1990, [32] which, like the Vienna Convention, requires each party to adopt legislation that criminalizes money laundering.
For the majority of physicians to adopt a new technology in their private office practice, that technology must address three major issues: (1) money, (2) hassle, and (3) patient care.
Known as attachment disorder, this condition has attracted intense interest as more people adopt institutionalized youngsters from around the world.
The family had also agreed to adopt Matthew's brother, 6-year-old Joseph, who had spent most of his life in the state's "care.