ADOPT


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ADOPT

Cardiology
Accupril Decision On PharmacoTherapy. A clinical trial that was planned at Vanderbilt University in Tennessee, the purpose of which was to compare efficacy and safety of quinapril, enalapril, atenolol and verapamil in controlling blood pressure in patients with uncomplicated mild to moderate hypertension when used as single-agent therapy in a structured titration program.
 
Endocrinology
A Diabetes Outcome Progression Trial. A 4-year Phase-4 trial comparing early treatment of type-2 diabetics with rosiglitazone (Avandia), metformin or glyburide (a sulfonylurea in glucose control) for delay or prevention of diabetes complications—e.g., kidney disease, etc.

Conclusion
Lower failure rate at 5 years: 15% with rosiglitazone vs. 21% with metformin and 34% with glyburide; a highly significant risk reduction of 32% for rosiglitazone compared with metformin, and 63% compared with glyburide. Positive results notwithstanding, rosiglitazone has been pulled from various markets due to possible increased risk of heart attacks.

ADOPT

Endocrinology A 4-yr phase IV trial–A Diabetes Outcome Progression Trial–comparing early treatment of Pts with type 2 DM with Avandia®, metformin, or glyburide–a sulfonylurea in glucose control, delay or prevention of DM complications–eg, kidney disease, etc
References in periodicals archive ?
Thank you so very much for supporting and believing in a dream, the Adopt a Teacher Program.
Flint: We were looking to adopt and we knew there was a need for parents to adopt African American children.
Children with an adoptive stepparent enjoy other benefits not available to children living with a same-sex parent who is unable to adopt.
Another parent expressed the belief that extra "pull" was needed to adopt through an agency.
The legislative history supports this reading of the text by demonstrating that Congress intended to adopt the SEC's regulatory definitions of the prohibited services, including the definitions of appraisal, valuation, and actuarial services, and the definitional exceptions for tax ser vices.
And Davies also believes that many celebrities who adopt simply want to use their position to help children who may be disabled or orphaned, something which she thinks may be behind Jolie's decision to care for a Cambodian child.
37] The jurisdictions (noncooperating countries) [38] either failed to adopt meaningful legislation criminalizing laundering or have serious deficiencies in their banking laws and implementing regulations.
Few of these incentives exist to encourage physicians to adopt new technology.
Even then, it may take longer for all of the states to adopt the provisions.
The Rainforest Alliance (RA) program, also called Adopt an Acre, sends donations either to El Salvador's SalcaNATURA or to Colombia's Natura Foundation, both respected on-the-ground groups.
The family had also agreed to adopt Matthew's brother, 6-year-old Joseph, who had spent most of his life in the state's "care.
In so holding, the court rejected Muncy's argument that its ruling would allow Harrison Radiator to adopt one of his suggestions but not pay him for it.