attention deficit-hyperactivity disorder type 7

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attention deficit-hyperactivity disorder type 7

A clinically variable form (OMIM:613003) of ADHD, a neurobehavioural developmental disorder primarily characterised by the coexistence of attentional problems and hyperactivity.

Molecular pathology
Caused by defects of TPH2, which encodes tryptophan hydroxylase 2, an aromatic amino acid hydrolase that catalyses the first and rate-limiting step in serotonin synthesis.