ADH6

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ADH6

A gene on chromosome 4q23 that encodes class-V alcohol dehydrogenase, which like other alcohol dehydrogenases metabolises various substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids and lipid peroxidation products. It is expressed in the stomach and liver, and has a glucocorticoid response element upstream of its 5' UTR.
References in periodicals archive ?
The ADH-5 [TM] Multiplex IHC (Biocare Medical) supports the differentiation of UDH from ADH.
However, when Badve's team used a novel Multiplex IHC test containing high and low molecular weight cytokeratins and p63 (ADH-5, Biocare Medical), concordance among pathologists increased by 34%.
After native gel electrophoresis, the three isozymes of ADH, namely, ADH-5 (no NAD-acetone complex bound), ADH-3 (one-bound complex), and ADH-1 (both active sites occupied with NAD-acetone compounds), could be observed.
A comprehensive panel of antibodies for breast carcinoma includes ADH-5 (atypical ductal hyperplasia).