ADAMTSbg16

(redirected from ADAMTS-16)

ADAMTSbg16

An ADAMTSs family enzyme encoded by ADAMTS16 on chromosome 5p15, which has high sequence similarity to the protein encoded by ADAMTS18. ADAMTS16 is expressed in fetal lung and kidney, and adult brain. Its overexpression in chondrosarcoma cells leads to decreased cell proliferation and migration, though not adhesion, as well as decreased MMP-13 expression.
References in periodicals archive ?
Moreover, the expression level of ADAMTS-16 was found to be higher in control placentas than in PE placentas Figure 2a, 2d).
In reference to genome-wide association studies, ADAMTS-16 has been perceived as a candidate locus linked with hypertension (29).
ADAMTS-17 and -19, ADAMTS-16 and -18, ADAMTS-7 and -12, and ADAMTS-6 and -10 compose the structurally related ADAMTS pairs division.