acetylcholine receptor

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Acetylcholine Receptor

A 250-kD nicotinic receptor which undergoes continuous turnover and renewal, a feature that explains the complete recovery of these receptors when damaged by autoimmune antibodies in myasthenia gravis.

acetylcholine receptor

An ion channel that opens when acetylcholine binds to it, so converting chemical diffusion into an electrical signal. Also known as the nicotinic acetylcholine receptor.
References in periodicals archive ?
Recent research suggests that the immune system attacks the postsynaptic ACh receptor sites and "clogs" or alters them with antibodies in such a way as to render them nonfunctional.
However, it is believed that a systemic autoimmune response is initiated by exposure to something chemically similar to the ACh receptor.
This compound acts as a reversible competitive AChE inhibitor, and an allosteric modulator of nicotinic ACh receptors (Schrattenholz et al.
Valeriana officinalis (valerian) is a herbal medicine traditionally used in the treatment of sleep disorders, anxiety, myalgia and epilepsy, with demonstrated anti-inflammatory actions, stimulatory effects on 5-HT and ACh receptors, and reduction of sleep-disturbance.
On the basis of the neuromuscular physiology described, muscle contraction may be blocked in the following two ways--competitive inhibition, the binding and blocking of the acetylcholine receptors without depolarization; and prolonged occupation and persistent binding of the Ach receptors, resulting in sustained depolarization of the neuromuscular junction.
Whether nicotinic ACh receptors are present on the motoneurons, and whether ACh represents input derived from the LBL or elsewhere in the squid brain, remains to be determined.
b) Valerian has demonstrated anti-inflammatory actions, stimulatory effects on 5-HT and Ach receptors, and reduction of sleep-disturbance
They therefore surmised that ACh would diffuse to the iridophore cell surfaces, would bind to ACh receptors there and thus would induce an ultrastructural change in the platelets to produce iridescence.