ACTN3

ACTN3

A gene on chromosome 11q13-q14 that encodes an actin-binding bundling protein expressed only in skeletal muscle, which localises to the Z-disc and analogous dense bodies, where it helps to anchor the myofibrillar actin filaments.
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The found genes related to resistance are ADRB2, 79C/G, BDKBR2, CHRM2, EpoR, HBB, HIF-1 [alpha], GYS1, NOS3, NRF2, PPAR5, VEGF; the ones related to strength, muscle mass and power are ace, ACTN3, AMPD1, CK-MM, IGF1.
Kawauchi possesses a variant of the widely studied ACTN3 gene -- the so-called speed gene.
(144.) See Nan Yang et al., ACTN3 Genotype Is Associated with Human
Investigation of the Relationship Between a Genetic Polymorphism in ACTN3 and Elite Sport Performance Among Iranian Soccer Players.
De Filippi et al .[28] reported that polymorphisms of the angiotensin-converting enzyme (ACE) and alpha-actinin 3 (ACTN3) could modulate the clinical symptoms of Pompe patients.
Among the candidate genes studied, the gene encoding [alpha]-actinin-3 (ACTN3) has been shown to be promising in studies that have a focus on training responses (23).
Estudos geneticos relacionam 23 genes capazes de influenciar o fenotipo da resistencia, dos quais o projeto DNA Olimpico enfoca dois, especificamente relacionados a performance fisica: a proteina alfa-actinina-3 (ACTN3) e a enzima conversora de angiotensina (ACE).
Abbreviations SNP - single nucleotide polymorphism ACE - angiotensin converting enzyme ACTN3 - alpha actinin 3 BRDKB2 - bradykinin receptor B2 GWAS - genome-wide association studies BASES - British Association of Sport and Exercise Sciences DNA - deoxyribonucleic acid The aim of training is achieving biological adaptation of the organism in line with its genetic potential, in order to accomplish specific tasks, with increased load.
Mutations in the gene ACTN3 are associated with the ability to run fast.
These genes include angiotensin 1 converting enzyme 1, alpha-actinin 3 (ACTN3), myostatin, ciliary neurotrophic factor, and vitamin D receptor.
Genetic associations of body composition, flexibility and injury risk with ACE, ACTN3 and COL5A1 polymorphisms in Korean ballerinas.