ACTH-producing adenoma

ACTH-·pro·duc·ing ad·e·no·ma

a pituitary tumor composed of corticotrophs that produce ACTH, often but not invariably a basophilic adenoma; may give rise to Cushing disease or Nelson syndrome.
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A bivariate plot based on principal components with an ellipse drawn around each K-means cluster is illustrated in Figure 1 for the validation set, which shows clustering of biologically relevant groups including gonadotroph adenomas adjacent to an IHC null cell group, Pit-1 family tumors, and ACTH-producing adenomas.