ACTG2


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ACTG2

A gene on chromosome 2p13.1 that encodes a gamma actin which coexists with beta actin as a cytoskeletal component and mediator of internal cell motility. Actin gamma 2 is found in enteric tissues.
References in periodicals archive ?
Genetic testing was performed on the mother and the infant, and they were both confirmed to have a novel heterozygous mutation in the ACTG2 gene (C632G>A, p.R211Q) on chromosome 2p13.1.
Visceral myopathy is a rare condition that has recently been attributed to mutations in the ACTG2 gene.
Primers for electron transfer flavoprotein subunit alpha, mitochondrial (ETFa), actin (ACTG2), transgelin (TAGLN), cofilin-1 (CFL1), cyclophilin A (PPIA), myosin (MYL6), galectin-1 (LGALS1), apolipoprotein A-I (APOA), and control genes ([sz]-actin) were obtained from Shanghai Sangon Company, China.
The primary antibodies used were rabbit anti-yactin (ACTG2) (GeneTex, GTX101794, 100-fold dilution); rabbit anti-myosin light chain kinase (MYLK) (Origene, TA347970, 400-fold dilution); rabbit anti-PP1[delta] (PPP1CB) (EMD Millipore, 07-1217, 100-fold dilution), Santa Cruz Biotechnology, Santa Cruz, CA, USA; rabbit anti-ROCK2 (sc-5561, 100-fold dilution); rabbit anti-CPI-17 (PPP1R14A) (sc-48406, 100-fold dilution); rabbit anti-pT38-CPI-17 (sc17560-R, 50-fold dilution); rabbit anti-myosin light chain (MYL9) (sc-15370, 500-fold dilution); anti-pS19-MYL9 (sc19849-R, 500-fold dilution); rabbit anti-MYPT1 (PPP1R12A) (sc-25618, 100-fold dilution); rabbit anti-pT853-MYPT1 (sc17432-R; 100-fold dilution); and rabbit anti pT696/MYPT1 (sc-.017556; 200-fold dilution).