ACIT system

ACIT system

Allogeneic cellular immune therapy system. A proprietary system for improving bone marrow transplant survival by inhibiting donor T-cells from causing GVHD, pretreating them with a light-activated psoralen (S-59) to prevent DNA and RNA replication, and treating donor T-cells to maintain their therapeutic properties.
References in periodicals archive ?
The company's ACIT system is being developed to improve engraftment of the bone marrow transplant and reduce serious adverse immune responses relating to bone marrow transplantation procedures.
The company's ACIT system has been developed to decrease the need for stringency of matching donors to patients and to inhibit the ability of donor T-cells to cause GVHD while maintaining their therapeutic properties.
The company's ACIT system is being developed to improve engraftment of the donor bone marrow and to reduce the occurrence of serious adverse reactions to the procedures, including graft-versus-host-disease (GVHD).
The company's ACIT system has been developed to inhibit the ability of donor T-cells to proliferate and cause GVHD while maintaining the therapeutic properties of these cells.
The company's ACIT system is being developed to improve transplant engraftment and reduce serious adverse immune responses relating to bone marrow transplantation procedures.
The company's ACIT system has been developed to decrease the stringency of matching donors to patients and to inhibit the ability of donor T-cells to cause GVHD while maintaining their therapeutic properties.