MACF1

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MACF1

A gene on chromosome 1p32-p31 that encodes F-actin-binding protein, which is thought to play a role in cross-linking actin to other cytoskeletal proteins and to microtubules. MACF1 plays a key role in ERBB2-dependent stabilisation of microtubules at the cell membrane, it upregulates the Wnt-receptor signalling pathway, and it is involved in translocating AXIN1 and its associated complex (composed of APC, CTNNB1 and GSK3B) from the cytoplasm to the cell membrane. It has actin-regulated ATPase activity and is essential for controlling focal adhesions (FAs) assembly and dynamics.

MACF1 may deliver transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with GOLGA4. It also plays a key role in wound healing and epidermal cell migration; it is required for efficient upward migration of bulge cells in response to tissue trauma, which reflects its ability to co-ordinate microtubule dynamics and polarise hair follicle stem cells.
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Only two students described themselves in terms of race or ethnicity, and one, ACF7 said she was "Americanized Hispanic.
ACF7 said that while the people in the business department had seemed cold and uncaring to her, [the professor] was welcoming which made her excited about joining the major.
In a similar train of thought, ACF7 said: "We should advertise ourselves better to students because if my advisor had never told me to call [the professor] I would never had known about this [major].
They want you to do well so they'll help you out any way they can, whether it's helping you out after class, even helping you out with simple things," ACF7 said.
The reason that I like ag journalism is because everyone knows each other, unlike other departments where there's like 5-600 kids in the major, there's only a handful of us so we get to know each other," ACF7 said.
While ACF7 talked about a friend from a summer internship, ACF5 and ACF3 mentioned friends from home.
Similarly, ACF7 said: "I see most of the people I know as friends .