Para este estudo, os idosos que relataram muita dificuldade ou que realizavam a atividade apenas com ajuda de outra pessoa ou aparelho foram considerados incapazes, para cada nivel (ABVD
, AIVD e mobilidade).
In both the Adcetris plus AVD and ABVD
arms, the most common Grade 3 or 4 events were neutropenia, febrile neutropenia and neutrophil count decrease.
A partir de los hallazgos del estudio es posible identificar perfiles de personas mayores que presenten una menor satisfaccion vital: en el caso de las mujeres aquellas que no conviven en pareja presentan deficiencia visual y/o auditiva, presentan autopercepcion de salud negativa, diagnostico de depresion en el ultimo ano y dificultades en las ABVD
The patient was diagnosed with Stage IVB Hodgkin's lymphoma and was started on ABVD
therapy (he eventually required a change in regimen from ABVD
to AVD due to bleomycin-induced pulmonary toxicity).
According to the company, the trial measured modified progression-free survival (mPFS), under which, about 117 (18%) patients on the Adcetris plus AVD arm who experienced disease progression, death, or began new therapy compared to 146 (22%) patients on the ABVD
The most common first-line treatment of classical HL is ABVD
, consisting of intensive dosing of doxorubicin, bleomycin, vinblastine, and dacarbazine.
Chemotherapy of advanced Hodgkin's disease with MOPP, ABVD
, or MOPP alternating with ABVD
Patient 2 received two cycles of rituximab and was defined as a non-response to treatment, additional diagnostic studies were performed with a splenectomy and liver biopsy, in which it was found Hodgkin lymphoma-like PTLD; therefore the patient received two cycles of ABVD
(Adriamycin, bleomycin, vinblastine and dacarbazine) with a partial response to treatment.
(Adriblastine 20 mg/[m.sup.2], Bleomycin 10 mg/[m.sup.2], Vinblastine 6 mg/[m.sup.2], Dacarbazine 375 mg/[m.sup.2]) therapy was started and the patient received a total of 6 cycles, with no hematologic toxicity and immediate clinical improvement after first cycle.
The patient had persistent fever during treatment with several lines of antibiotics (ciprofloxacin, levofloxacin, moxifloxacin, and piperacillin + tazobactam) and ABVD
I/1 (doxorubicin, bleomycin, vincristine, and dacarbazine).
She was initially treated with six cycles of doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD
) chemotherapy achieving complete radiological remission by PET (positron emission tomography) criteria.