Para este estudo, os idosos que relataram muita dificuldade ou que realizavam a atividade apenas com ajuda de outra pessoa ou aparelho foram considerados incapazes, para cada nivel (
ABVD, AIVD e mobilidade).
In both the Adcetris plus AVD and
ABVD arms, the most common Grade 3 or 4 events were neutropenia, febrile neutropenia and neutrophil count decrease.
A partir de los hallazgos del estudio es posible identificar perfiles de personas mayores que presenten una menor satisfaccion vital: en el caso de las mujeres aquellas que no conviven en pareja presentan deficiencia visual y/o auditiva, presentan autopercepcion de salud negativa, diagnostico de depresion en el ultimo ano y dificultades en las
ABVD y AIVD.
The patient was diagnosed with Stage IVB Hodgkin's lymphoma and was started on
ABVD therapy (he eventually required a change in regimen from
ABVD to AVD due to bleomycin-induced pulmonary toxicity).
According to the company, the trial measured modified progression-free survival (mPFS), under which, about 117 (18%) patients on the Adcetris plus AVD arm who experienced disease progression, death, or began new therapy compared to 146 (22%) patients on the
ABVD arm.
The most common first-line treatment of classical HL is
ABVD, consisting of intensive dosing of doxorubicin, bleomycin, vinblastine, and dacarbazine.
Chemotherapy of advanced Hodgkin's disease with MOPP,
ABVD, or MOPP alternating with
ABVD.
Patient 2 received two cycles of rituximab and was defined as a non-response to treatment, additional diagnostic studies were performed with a splenectomy and liver biopsy, in which it was found Hodgkin lymphoma-like PTLD; therefore the patient received two cycles of
ABVD (Adriamycin, bleomycin, vinblastine and dacarbazine) with a partial response to treatment.
Standard
ABVD (Adriblastine 20 mg/[m.sup.2], Bleomycin 10 mg/[m.sup.2], Vinblastine 6 mg/[m.sup.2], Dacarbazine 375 mg/[m.sup.2]) therapy was started and the patient received a total of 6 cycles, with no hematologic toxicity and immediate clinical improvement after first cycle.
The patient had persistent fever during treatment with several lines of antibiotics (ciprofloxacin, levofloxacin, moxifloxacin, and piperacillin + tazobactam) and
ABVD I/1 (doxorubicin, bleomycin, vincristine, and dacarbazine).
She was initially treated with six cycles of doxorubicin, bleomycin, vinblastine, and dacarbazine (
ABVD) chemotherapy achieving complete radiological remission by PET (positron emission tomography) criteria.