APP

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APP

amyloid precursor protein.

APP

abbr.
amyloid precursor protein

amyloid precursor protein (APP)

a large transmembrane glycoprotein expressed on the cell surface and of uncertain function; it may be cleaved on the cell surface to a soluble form. Alternatively, cleavage may follow endocytosis and in some cases then yields 40 to 43 abnormal amino acid peptides, which aggregate to form Ab amyloid, associated with Alzheimer's disease.

APP

A gene on chromosome 21q21.3 that encodes a cell surface receptor and transmembrane precursor protein which is cleaved by secretases to form various peptides.

Molecular pathology
APP mutations are implicated in autosomal dominant Alzheimer’s disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).

APP

Amyloid β protein precursor A membrane-spanning glycoprotein of unknown function, which is expressed in many mammalian tissues, the gene for which maps to chromosome 21. See Alzheimer's disease, β-amyloid.
References in periodicals archive ?
I should note that this situation has been faced by other ABPP specialties as well.
ABPP, 8927 Hypoluxo Road, Bldg A-4, #224, Lake Worth, FL 33467.
Bryan, PsyD, ABPP, 260 South Central Campus Drive, Room 205, Salt Lake City, UT 84105.
Carol Kauffman, PhD, ABPP, PCC, is director of the Institute of Coaching, McLean Hospital, Belmont, MA, and assistant clinical professor, department of psychiatry, Harvard Medical School.
Russo, PhD, ABPP (Diplomate of the American Board of Professional Psychology), is Chief Clinical Officer of May Institute.
Wayne Winkle, EdD, ABPP, is a Clinical/Administrative Officer at Western Arkansas Counseling and Guidance Center in Ft.
ABPP, FAASP The Cassel Institute Where Today is Tomorrow in Health Care 1362 Santa Cruz Court Chula Vista, California 91910
Norcross, PhD, ABPP, is an internationally recognized expert on behavior change and undisputed authority on New Year's resolutions.
Kanzler, PsyD, ABPP, Malcolm Grow Medical Clinic, JB Andrews, MD; Jeffrey L.
This July we are privileged to have Gerald Corey, EdD, ABPP, present on the latest in ethical issues, and Leslie Lundt, MD, will offer a presentation on psychopharmacology.
Christian, PhD, ABPP, who is largely responsible for the exponential growth of the organization over the past 30 years, opening the Southeast Regional Autism Center in close proximity to Fort Benning, was both a personal and a professional decision.
Frederick Rotgers, PsyD, ABPP, associate professor of psychology at the Philadelphia College of Osteopathic Medicine, is seeking program directors willing to complete an anonymous survey on informed consent practices in addiction treatment facilities.