FLNC

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FLNC

A gene on chromosome 7q32-q35 that encodes filamin gamma (filamin C), a muscle-specific actin-binding protein that crosslinks actin filaments into orthogonal networks in cortical cytoplasm and anchors membrane proteins to the actin cytoskeleton. It is critical for normal myogenesis and for maintaining the structural integrity of the muscle fibres.

Molecular pathology
Defects in FLNC cause myofibrillar myopathy type 5 and myopathy distal type 4.
References in periodicals archive ?
Outlook on the assigned ratings has been revised from stable to positive as JCR-VIS expects continued momentum in the recovery of financial indicators of the bank to translate into improved positioning of ABPL vis-a-vis peer banks, going forward.
With assets in excess of Rs67 billion; a workforce of 1,400 professionals and a network of 94 branches in 42 cities and towns across Pakistan, ABPL is also devoted in providing customers with a range of Shariah compliant products to suit their banking needs.
ABPL is a part of Al Baraka Banking group (ABG), the leading international Islamic banking group in the gulf region.