ABO system

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Related to ABO blood group system: Rh factor, blood transfusion

ABO system

(ā′bē-ō′)
n.
A classification system for human blood that identifies four major blood types based on the presence or absence of two antigens, A and B, on red blood cells. The four blood types (A, B, AB, and O, in which O designates blood that lacks both antigens) are important in determining the compatibility of blood for transfusion.

ABO System

The major alloantigen system in humans, which is based on 3 carbohydrate antigens expressed on red cells, encoded on chromosome 9q34. 
Significance ABO blood groups determine to whom one can donate blood from whom one can accept blood. Type A or AB blood causes an immune reaction in type Bs. Type B and AB blood cause an immune reaction in type As. Conversely, type O blood has no A or B antigens—type Os are universal donors. Since AB blood already produces both antigens, type ABs can accept any of the other blood types without suffering an immune reaction, and are thus known as universal recipients, as they form antibodies to neither A nor B antigens.

ABO system

ABO blood group system Transfusion medicine The major alloantigen system in humans, based on 3 carbohydrate antigens expressed on RBCs, encoded on chromosome 9q34 Significance ABO blood groups determine who can donate blood to, or accept blood from, whom; type A or AB blood causes an immune reaction in type Bs; type B and AB blood cause an immune reaction in type As; conversely, type O blood has no A or B antigens–type Os are universal donors; since AB blood already produces both antigens, type ABs can accept any of the other blood types without suffering an immune reaction, and are thus known as universal recipients, as he/she forms antibodies to neither A nor B antigens. See Blood group antigens, Lewis antigen, Transplantation, Universal donor, Universal recipient.
References in periodicals archive ?
(2004) conducted a study to record the prevalence of ABO blood group system in Bannu region NWFP.
ABO blood group system and placental malaria in an area of unstable malaria transmission in eastern Sudan.
Karl Landsteiner determined the ABO blood group system first time in 1901.
This is the birthdate of Karl Landsteiner, who discovered the ABO blood group system.
The ABO blood group system was the first polymorphism in genetics discovered in human being.[20] Due to the importance of ABO blood group system in transfusion medicine and organ transplantation,[21] it has been immensely studied in relation to various diseases.
Out of 158 cases of HDFN, 110 occurred due to antibodies against antigens in ABO blood group system. In ABO-HDFN, 92 (58.2% of total) cases were due to anti-A and 18 (11.4% of total) cases were due to anti-B.
World Blood Donor Day is observed on the birthday of Karl Landsteiner (June 14,1868), who created the ABO blood group system, which is still used today to ensure the safety of blood transfusions.
The antigens of the ABO blood group system (A, B, and H determinants, respectively) are complex carbohydrate molecules on the extracellular surface of RBC membranes.
On the other hand absence of ABH substances in intestinal and urogenital tract secretions allow microorganisms adherence and increase the risk of duodenal ulcer celiac disease urinary tract infections and persistent candida infections.11Frequency of secretors and non-secretors of ABO blood group system has not been determined yet in Pakistan.
The ABO blood group system. Modern blood banking & transfusion practices.
[6] Therefore, the ABO blood group system influences the bleeding time (BT) and clotting time (CT).
Conclusion: This study confirmed that blood group O was the most common of the ABO blood group system in the Jazan region.