Also found in: Acronyms.


A gene on chromosome 13q22 that encodes endothelin-B receptor, a member of the endothelin receptor group of G-protein-coupled
receptors, located primarily in the vascular endothelial cells where they play a role in vasoconstriction, vasodilation, bronchoconstriction and cell proliferation.

Molecular pathology
EDNRB mutations cause Hirschsprung disease type 2.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
The ABCDs are involved not only in the trading of food commodities, but also in their production and storage and, increasingly, investment in the industry.
"Today, banks and other investors, as well as dedicated investment funds established as subsidiaries of the ABCDs themselves, have invested billions of dollars in food commodities with no interest in taking possession of any physical commodity," the report reads.
This is what is referred to as the "financialization" of the food commodities market, which essentially means that the ABCDs have a great deal of control in influencing the prices of the products they are trading in, as well as the ability to hedge on their investments to forestall market volatility.
This is particularly troublesome in times of low food production -- which is becoming more common as climate change causes worse droughts and harsher weather conditions -- because the ABCDs have no incentive to keep food prices affordable despite humanitarian concerns.
The ABCD criteria function well on their own in detecting melanoma in pigmented lesions larger than 6 mm in diameter, the dermatologist noted.
Friedman looks for pigmented lesions with evolving ABCD criteria by analyzing the photos of a patient's lesions on a computer (usually twice per year).
Friedman uses a dermatoscope to examine patients who have lesions evolving with at least some of the ABCD criteria.
ABCD is supported by the National Institute on Alcohol Abuse and Alcoholism, the National Institute on Drug Abuse, the National Cancer Institute, the Eunice Kennedy Shriver National Institute of Child Health and Human Development, the National Institute of Mental Health, the National Institute on Minority Health and Health Disparities, the National Institute of Neurological Disorders and Stroke, the NIH Office of Behavioral and Social Sciences Research, and the Division of Adolescent and School Health at the Centers for Disease Control and Prevention.
The ABCD acronym, launched in 1985, is a form of gross clinical analysis that "has served us well" in the early recognition of melanoma, Dr.
Also, the ABCD criterion does not fit for many thin melanomas.
That 85% sensitivity when the ugly duckling sign was applied by non-clinicians is much higher than the percentage seen in studies of the ABCD method, Dr.