ABCC1

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ABCC1

A gene on 16p13.1 that encodes a protein of the MRP subfamily of the superfamily of ATP-binding cassette (ABC) transporters, which transport various molecules across extra- and intracellular membranes, many of which are involved in multidrug resistance. ABCC1 is a transporter of multispecific organic anions, glucuronides and sulfate conjugates of steroid hormones and bile salts; it mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, methotrexate, antivirals and other xenobiotics, and confers resistance to anticancer drugs.
References in periodicals archive ?
To this end, I am indebted for the support extended to QDB by both the Ambassador of Qatar to Brazil, H E Mohammed bin Ahmad Al Haiki, and CEO of the ABCC, Michel Alaby.
Has ABCC ever received any complaints from Brazilian companies operating in the Egyptian market?
The government had refused to countenance any of the substantive changes proposed by the Senate crossbench to its bill to reA[degrees]establish the ABCC and Turnbull had proA[degrees] rogued parliament on the basis that if it did not pass the industrial bills he would call an election for the House of Representatives and the full Senate after the May 3 budget, to be held on July 2.
We're looking at any and all forms of inducements,'' said Frederick Mahoney, chief investigator for ABCC.
From that modest beginning, ABCC, as it is known, has grown to attract 200 to 550 participants to its annual conferences.
Together with 23,500 member firms nationally, the ABCC is a group of contractors, suppliers and industry professionals seeking to promote and improve the image of and address the many issues facing the construction industry.
8 billion ($500 million), the ABCC in conjunction with the Brazilian government has begun a campaign to fly some of the Middle East's biggest coffee importers and a select group of food and beverage companies to the 'Expodireto Cotrijal' agricultural fair being held in the Brazilian state of Rio Grande do Sul.
Commenting on Qatari investments in Brazil, the ABCC chief said, "There is a bulk of Qatari investments in Brazil, with plans to launch more in the future.
AmerisourceBergen, which retained its Canadian specialty drug business, said that ABCC accounted for about 2% of the company's total revenue.
6 per cent on the equivalent period a year ago, according to ABCC data.
He said: "The long list of brilliant projects ABCC is involved in is testament to the hard work, dedication and creativity of all those involved.
The State ABCC claimed that the voucher promotion violated both the state's happy hour promotion regulations (by offering beverage alcohol at too great a discounted price) and the state's beverage alcohol licensing regulations (by creating an interest for Groupon in the licensed business of the restaurant).