SLC25A5

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SLC25A5

A gene on chromosome Xq24 that encodes a mitochondrial solute carrier protein, which functions as a gated pore that translocates ADP from the mitochondrial matrix into the cytoplasm. SLC25A5 forms a
homodimer embedded in the inner mitochondria membrane. Suppressed SLC25A5 expression induces apoptosis and inhibits tumour growth.
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Amount of different constituents DMF CA AAc Crosslinker initiator Sample codes (mL) (mg) (mM) (MB) (mM) (BP) (mM) CA (0) 3 0 13.87 0.648 0.548 MB1 3 60 13.87 0.454 0.548 MB2 3 60 13.87 0.978 0.548 CA1 3 30 13.87 0.648 0.548 CA2 3 90 13.87 0.648 0.548 AAc1 3.7 60 4.163 0.648 0.548 AAc2 3.3 60 9.71 0.648 0.548 % yield = ([M.sub.AAC] + [M.sub.MB] + [M.sub.CA])/[M.sub.total] x 100 (1)
To evaluate the above parameters, six semi-IPN samples, namely MB1 and MB2, CA1 and CA2 and AAc1 and AAc2 were prepared (see Table 1 for composition of these samples) and were allowed to equilibrate in the phosphate buffer media of pH 7.4 for a period of 24 h at 37[degrees]C.
Samples Crosslink density [V.sub.e] x Crosslink [M.sub.c] [10.sup.-20] density q x [10.sup.4] CA(0) 1.01 28.26 25497 MB1 0.13 16.9 42430 MB2 4116.9 10030 23400 CA1 0.066 5.75 125300 CA2 42190 41.72 17271.41 AAc1 0.4 x [10.sup.20] 34 21571.25 AAc2 60260.8 x [10.sup.20] 50.4 1492.67 Kinetic Water Uptake Studies
The dynamic water absorption behavior of samples MB I and MB2; CA(0), CAI and CA2 ; and AAc1 and AAc2 was investigated in the phosphate buffer medium of pH 7.4 at 37[degrees]C.
The dynamic water absorption data of all six samples, namely MB1, MB2, CAI, CA2, AAcl, and AAc2 were analyzed using the following power-law, given by Peppas (25):
sub.-1) sup-1] -1]) CA (0) 0.77 4.68 1.7 3.63 121.7 MBI 0.72 6.4 1.6 5.52 120.5 MB2 0.61 11.95 1.7 8.68 109.4 CAI 0.65 8.84 1.5 7.24 118.5 CA2 0.53 14.68 1.2 5.19 94.16 A Ac 0.51 179.17 1.7 3.16 101.68 AAc2 0.68 7.4 1.5 4.93 94.83 The kinetic uptake data was also applied on the First order kinetic equation, developed by Beren and berg (27), according to which the rate of water uptake at any time is proportional to the first power of the amount of water to be absorbed to attain equilibrium i.e.