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A gene on chromosome 21q21.3 that encodes a cell surface receptor and transmembrane precursor protein which is cleaved by secretases to form various peptides.

Molecular pathology
APP mutations are implicated in autosomal dominant Alzheimer’s disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).


Amyloid β peptide
References in periodicals archive ?
CAD-0205 measures approximately half the size of A4 paper, so its compact footprint means it can be placed anywhere in the office.
The 204-page work, on quality A4 paper, is a major work by renowned author Malcolm Handley and is published by Tallis Associates.
Summary: A total of 253 athletes from 83 nations pushed the limits of physics with nothing more than a sheet of standard A4 paper this weekend as Red Bull Paper Wings returned after its successful debut in 2006.
They also used more than 112 million pages of A4 paper.
Again, your review must be written in double spacing on one side of A4 paper with your name, address and phone number.
Made in Criterion's state-of-the-art manufacturing facility in East Tamaki, Concorde's ergonomic design incorporates sleek curves, wrap around desktops and 'comfort edges' Combined with the 'screen pack' accessories package (includes utility tray, penholder, phone tray, file holder and A4 paper tray) the rang-keeps essentials hand and desk clutter at bay.
These are but three ticks on an incredibly long list of obsessive-compulsive tasks he set for himself early on, and such works were often installed in what seemed a send-up of Conceptual art formats: cheap booklets, sweeps of A4 paper and snapshots gridded on the wall.
Submissions may be accompanied by a written report of a maximum of 500 words on A4 paper.
5 x 11 inch and A4 paper sizes, the BPRF is also capable of supporting paper sizes up to 11 x 17 inches.
Contract notice: successive supply of white a4 paper
A PUBLICAN criticised "heavy-handed" officials for taking her to court for having hand-written no-smoking signs on A4 paper.
THE slim black device, pictured, is slightly smaller than a piece of A4 paper.