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A gene on chromosome 21q21.3 that encodes a cell surface receptor and transmembrane precursor protein which is cleaved by secretases to form various peptides.

Molecular pathology
APP mutations are implicated in autosomal dominant Alzheimer’s disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).


Amyloid β peptide
References in periodicals archive ?
First, draw a template on a page of A4 paper for big, medium and small triangles.
HAS Apple released the new iPad disguised as a wad of A4 paper?
All entries must be on A4 paper and can be sent to: Lisa Stirling, Nuneaton and Bedworth Firework Safety Competition, Warwickshire Trading Standards Service, Old Budbrooke Road, Warwick CV35 7DP.
The 204-page work, on quality A4 paper, is a major work by renowned author Malcolm Handley and is published by Tallis Associates.
In one hospital branch, a bottle of still mineral water is on sale for pounds 1.69, compared to 85p in the city centre while a pounds 1.99 pad of A4 paper is pounds 1 dearer.
Applicants should be a Wales YFC member, aged 16-26, and describe the changes they have experienced in Welsh sheep farming, look at the past, present and future of the industry and say how they would benefit from winning - all on two sides of A4 paper. Closing date is March 26.
That is equivalent to more than 20,000 sheets of A4 paper.
The PageStream 158 DC device offers 600 dpi highlight colour duplex printing as standard, at speeds of up to 158ppm on A4 paper. Other features include an ability to print on paper up to A3 size, printing of colours matched to the Pantone standard, an ability to operate simultaneously as a mainframe and a network printer and an input capacity of 10,000 sheets via up to eight input trays.
THE slim black device, pictured, is slightly smaller than a piece of A4 paper.
So he dashed off the caricature of her - a female figure with huge breasts, hips and lips - using a black biro and a piece of A4 paper. The artist then wrote "Can't live with 'em, can't live with 'em" and signed the sketch "Love Damien Hirst".
The scripts, which were written in 1976 on 56 pages of A4 paper, are expected to fetch thousands of pounds when they are sold next month.