A2058

A2058

A cell line established from a melanoma metastasis of a 43-year-old. The cells are highly invasive and are a source of proteins (e.g., autocrine motility factor (AMF)—autotaxin) associated with invasion—e.g., interstitial collagenase, TIMP-2.
References in periodicals archive ?
These are genes related to the expression of this phenotype, making the modification in the binding target due to the methylation of residue A2058, locatedin the V domain of 23s (Naimi et al.
Briefly, MDA-MB-231 cells, A2058, SIHA, SK-Mel-28 and MCF-7([10.
EUG showed to induce PS exposition in MDA-MB-231, MCF-7, and A2058 cells.
Alterations in cytoplasm membrane were identified on A2058 and MDA-MB-231; however these cells maintained their adherence.
The A2058 cell line showed a high clastogenic index even before EUG treatment.
S2 (BCRC number 60263), A2058 (BCRC number 60240), and B16-F10 (BCRC number 60031).
S2 comprised cells which were differentiated from A375 cells; and cell line A2058 comprised highly invasive melanoma cells [21].
Douthwaite, "Resistance to the macrolide antibiotic tylosin is conferred by single methylations at 23S rRNA nucleotides G748 and A2058 acting in synergy," Proceedings of the National Academy of Sciences of the United States of America, vol.
The assessment of the mt in cells conducted by the authors indicated that A2058 cells treated with dosages higher than 0.
Honeybee venom induces calcium-dependent but caspase-independent apoptotic cell death in human melanoma A2058 cells.
Mutations of A2058, A2059, and other 23S rRNA residues within the macrolide-binding site can confer a high-level resistance to macrolides in several bacterial species, including M.