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ATP6V0A2

A gene on chromosome 12q24.31 that encodes a subunit of H+-ATPase (also known as V-ATPase, vacuolar ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles, which is required for an array of molecular processes, including protein sorting, zymogen activation, receptor-mediated endocytosis and synaptic vesicle proton gradient generation.

Molecular pathology
ATP6V0A2 mutations cause cutis laxa type II and wrinkly skin syndrome.
References in periodicals archive ?
Credit enhancement (CE) of 38.8%, 35.0% and 25.5% for class A-1, A-2 and B-1 notes, respectively, in addition to excess spread, is sufficient to protect against portfolio default and recovery rate projections in their respective rating stress scenarios.
Credit enhancement (CE) of 43.0% for class A-1 notes and 36.3% for class A-2 notes, in addition to excess spread, is sufficient to protect against portfolio default and recovery rate projections in a 'AAAsf' stress scenario for class A-1 and A-2 notes.
20 October 2011 - S&P on Wednesday attached its A-2 short-term corporate credit rating to US gas transportation and storage firm Spectra Energy Partners LP (NYSE:SEP).
Credit enhancement (CE) of 41.3% and 36.0% for class A-1 and A-2 notes, respectively, in addition to excess spread, is sufficient to protect against portfolio default and recovery rate projections in a 'AAAsf' stress scenario.
Credit enhancement (CE) of 38.0% and 35.0% for class A-1 and A-2 notes (together, class A notes), respectively, in addition to excess spread, is sufficient to protect against portfolio default and recovery rate projections in the 'AAAsf' stress scenario.
BANKING AND CREDIT NEWS-August 26, 2011--S&P sets A-2 rating to NBCUniversal Media(C)2011 M2 COMMUNICATIONS http://www.m2.com
M2 EQUITYBITES-August 26, 2011--S&P sets A-2 rating to NBCUniversal Media(C)2011 M2 COMMUNICATIONS http://www.m2.com
Securities and Exchange Commission, assigned the following ratings and Rating Outlooks to OHA Credit Funding 1, Ltd.: --$292,000,000 class A-1 notes 'AAA(EXP)sf'; Outlook Stable; and --$30,500,000 class A-2 notes 'AAA(EXP)sf'; Outlook Stable.
These are as follows:--$240,000,000 class A-1 notes 'AAAsf'; Outlook Stable; and --$16,000,000 class A-2 notes 'AAAsf'; Outlook Stable.
These are as follows:--$320,000,000 class A-1 notes 'AAAsf'; Outlook Stable; and --$57,500,000 class A-2 notes 'AAsf'; Outlook Stable.