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ATP6V0A2

A gene on chromosome 12q24.31 that encodes a subunit of H+-ATPase (also known as V-ATPase, vacuolar ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles, which is required for an array of molecular processes, including protein sorting, zymogen activation, receptor-mediated endocytosis and synaptic vesicle proton gradient generation.

Molecular pathology
ATP6V0A2 mutations cause cutis laxa type II and wrinkly skin syndrome.

References in periodicals archive ?

Credit enhancement (CE) of 38.8%, 35.0% and 25.5% for class A-1, A-2 and B-1 notes, respectively, in addition to excess spread, is sufficient to protect against portfolio default and recovery rate projections in their respective rating stress scenarios.

Fitch Ratings assigns ratings to Buttermilk Park CLO, Ltd

Credit enhancement (CE) of 43.0% for class A-1 notes and 36.3% for class A-2 notes, in addition to excess spread, is sufficient to protect against portfolio default and recovery rate projections in a 'AAAsf' stress scenario for class A-1 and A-2 notes.

Fitch Ratings assigns ratings to Madison Park Funding XXIX, Ltd

20 October 2011 - S&P on Wednesday attached its A-2 short-term corporate credit rating to US gas transportation and storage firm Spectra Energy Partners LP (NYSE:SEP).

-Spectra Energy Partners gets short-term rating of A-2 from S&P

Credit enhancement (CE) of 41.3% and 36.0% for class A-1 and A-2 notes, respectively, in addition to excess spread, is sufficient to protect against portfolio default and recovery rate projections in a 'AAAsf' stress scenario.

Fitch Ratings assigns ratings to Octagon Investment Partners 38, Ltd

Credit enhancement (CE) of 38.0% and 35.0% for class A-1 and A-2 notes (together, class A notes), respectively, in addition to excess spread, is sufficient to protect against portfolio default and recovery rate projections in the 'AAAsf' stress scenario.

Fitch Ratings to assign ratings to Dryden 65 CLO, Ltd

-S&P sets A-2 rating to NBCUniversal Media

Securities and Exchange Commission, assigned the following ratings and Rating Outlooks to OHA Credit Funding 1, Ltd.: --$292,000,000 class A-1 notes 'AAA(EXP)sf'; Outlook Stable; and --$30,500,000 class A-2 notes 'AAA(EXP)sf'; Outlook Stable.

Fitch Ratings assigns ratings to OHA Credit Funding 1, Ltd

These are as follows:--$240,000,000 class A-1 notes 'AAAsf'; Outlook Stable; and --$16,000,000 class A-2 notes 'AAAsf'; Outlook Stable.

Fitch Ratings assigns ratings to MidOcean Credit CLO IX

These are as follows:--$320,000,000 class A-1 notes 'AAAsf'; Outlook Stable; and --$57,500,000 class A-2 notes 'AAsf'; Outlook Stable.