A1

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A1

A member of the Bcl-2 protein family encoded by BCL2A1, which counteracts apoptosis by growth-factor withdrawal. A1 expression permits accumulation of differentiated myeloid cells both before and after IL3 withdrawal. Murine A1 is a homolog of human BFL-1.
References in periodicals archive ?
The rating of the classes A-1 and A-2 notes addresses the likelihood that investors will receive timely and compensating interest payments, as well as the stated balance of principal by the final payment date.
66,950,000 revenue refunding bonds, senior 2002 series A-1 at 'AAA';
67,200,000 revenue refunding bonds, senior 2003 series A-1 at 'AAA';
Due to the increased credit enhancement levels and the positive rating migration within the collateral pool, Fitch affirms the A-1 and A-2 classes, and upgrades all other classes.
A notable feature of the structure includes the use of a delayed draw mechanism for the class A-1 notes.
Interest payments are made on a sequential basis, paid first to the class A-1 notes.