methoxsalen

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methoxsalen

 [mĕ-thok´sah-len]
an acrylic acid compound that induces melanin production on exposure of the skin to ultraviolet radiation; used orally and topically in the treatment of idiopathic vitiligo, mycosis fungoides, and psoriasis.

methoxsalen

A photosensitising psoralen that is given systemically or topically before the skin is exposed to UV light, as part of treatment for psoriasis, eczema, vitiligo and some cases of cutaneous lymphoma.

methoxsalen

Oxsoralen® Dermatology A photosensitizing psoralen, given systemically or topically, after which the skin is exposed to UV light. See Psoriasis, PUVA.
References in periodicals archive ?
Here, we demonstrated that UVADEX (8-MOP) treatment, combined with UV-irradiation, is able to inactivate known insect viruses and that UVADEX treatment does not decrease APC function.
8-MOP (UVADEX) is one of the psoralen derivatives commonly being used for the inactivation of a variety of viruses in a blood product.
Cases Sex Age Why the treatment (year-old) of PUVA was given 1(2) Female 45 Vitiligo 2(3) Male 50 Psoriasis 3(4) Male 80 Psoriasis 4(5) Female 57 Mycosis fungoides 5(6) Female 65 Psoriasis 6(7) Female 67 Psoriasis 7(8) Male 58 Psoriasis 8(9) Male 61 Psoriasis 9 (present Female 26 Mycosis fungoides case) Cases Type of UVA 1(2) Topical PUVASOL 2(3) Oral PUVA (methoxsalen) 3(4) Oral PUVA (5-MOP) 4(5) Oral PUVA (8-MOP) 5(6) Oral PUVA (8-MOP) 6(7) UVA 7(8) PUVA (unspecified) 8(9) Oral PUVA (oxsoralen) 9 (present Oral PUVA (8-MOP) case)
Methoxsalen (8-MOP) is a molecule found in the plant Ammi majus, which remains biologically inert unless exposed to ultraviolet radiation (4).
Twenty-one healthy volunteers [either untreated or treated with oral psoralens (8-MOP or 5-MOP)] were enrolled in this study and exposed to solar radiation for evaluation of the following clinical parameters: immediate pigment darkening (IPD), minimal erythema dose (MED), minimal melanogenic dose (MMD), and minimal phototoxic dose (MPD) before and after topical or oral administration of PL.
As a positive control, four filter disks were each impregnated with 600 [micro]g of the photosensitizing agent 8-methoxypsoralen (8-MOP) (Sigma-Aldrich, St.
During photopheresis, the person first takes an oral compound called 8-methoxypsoralen (or 8-MOP) that makes the body's cells sensitive to light.