CCL21

(redirected from 6Ckine)

CCL21

A gene on chromosome 9p13 that encodes a CC-type cytokine, which is characterised by two adjacent cysteines and, as with all cytokines, is involved in immunoregulatory and inflammatory processes. CCL21 binds CCR7, inhibits haemopoiesis and is chemotactic for thymocytes and activated T cells—but not B cells, macrophages or neutrophils; it may also play a role in homing lymphocytes to secondary lymphoid tissue.
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Capucilli, MD (Fellow-in-Training), Children's Hospital of Philadelphia, for his abstract entitled "A Comparison of Comorbid Diagnoses in Children with and without Eosinophilic Esophagitis in a Large Primary Care Population," and Ichiro Nomura, MD (Member), National Research Institute for Child Health and Development, for his abstract entitled "Elevated Serum TSLP, IL-33, 6Ckine and MCP-3 Levels in School Children or Older Patients with Eosinophilic Gastroenteritis.