CCL21

(redirected from 6Ckine)

CCL21

A gene on chromosome 9p13 that encodes a CC-type cytokine, which is characterised by two adjacent cysteines and, as with all cytokines, is involved in immunoregulatory and inflammatory processes. CCL21 binds CCR7, inhibits haemopoiesis and is chemotactic for thymocytes and activated T cells—but not B cells, macrophages or neutrophils; it may also play a role in homing lymphocytes to secondary lymphoid tissue.
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Capucilli, MD (Fellow-in-Training), Children's Hospital of Philadelphia, for his abstract entitled "A Comparison of Comorbid Diagnoses in Children with and without Eosinophilic Esophagitis in a Large Primary Care Population," and Ichiro Nomura, MD (Member), National Research Institute for Child Health and Development, for his abstract entitled "Elevated Serum TSLP, IL-33, 6Ckine and MCP-3 Levels in School Children or Older Patients with Eosinophilic Gastroenteritis."
2018 AAAAI/APFED Best Abstract on EGIDs Awards Recipients Announced
Group I- Group II- preterm labor false preterm labor n = 62 n = 47 Chemokines concentration (pg/mL) Median (min-max) 6Ckine 11539 (2713-77761) 12543 (3226-39407) Axl 1306 (529.5-7509) 1389 (601.4-3074) BTC 8924 (5577-32195) 8246 (5383-18495) CCL28 13504 (7193-41772) 13959 (7923-78508) CTACK/CCL27 3831 (1028-93251) 4138 (1006-25364) CXCL16 2849 (1789-7924) 2844 (1260-13175) ENA-78/CXCL5 2894 (380.8-16116) 2728 (799.4-19843) Eotaxin-3 4545 (2229-18529) 4269 (1507-23502) GCP-2 709.7 (132.1-2507) 743.8 (190-1841) GRO [alpha].
Chemokines profiling of patients with preterm birth
On the other hand, in the same amniotic fluid of fetuses with Down syndrome, as compared with control, we observed a significant increase in the concentration of 4 chemokines: 6Ckine, IP-10, MPIF-1, and CXCL7 (Table 3).
Maternal plasma and amniotic fluid chemokines screening in fetal Down syndrome
McEvoy, "The CC chemokine receptor-7 ligands 6Ckine and macrophage inflammatory protein-3[beta] are potent chemoattractants for in vitro- and in vivo-derived dendritic cells," Journal of Immunology, vol.
Immunomodulation by Trypanosoma cruzi: toward understanding the association of dendritic cells with infecting TcI and TcII populations

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