PDE1A(redirected from 61-kDa Cam-PDE)
PDE1AA gene on chromosome 2q32.1 that encodes a cyclic nucleotide phosphodiesterase, which plays a critical role in signal transduction, regulating intracellular cyclic nucleotide concentrations by hydrolysing cAMP and/or cGMP to AMP and GMP. As with other PDE1s, PDE1A is activated by calmodulin in the presence of Ca2+.
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