reductase

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reductase

 [re-duk´tās]
an enzyme that catalyzes a chemical reduction.
5α-reductase an enzyme that catalyzes the irreversible reduction of testosterone to dihydrotestosterone.

re·duc·tase

(rē-dŭk'tās),
An enzyme that catalyzes a reduction; because all enzymes catalyze reactions in either direction, any reductase can, under the proper conditions, behave as an oxidase and vice versa, hence the term oxidoreductase. For individual reductases, see the specific names.
Synonym(s): reducing enzyme

reductase

/re·duc·tase/ (-tās) a term used in the names of some of the oxidoreductases, usually specifically those catalyzing reactions important solely for reduction of a metabolite.
5α-reductase  an enzyme that catalyzes the irreversible reduction of testosterone to dihydrotestosterone; enzyme deficiency leads to a form of male pseudohermaphroditism.

reductase

(rĭ-dŭk′tās′, -tāz′)
n.
Any of various enzymes that catalyze the reduction of an organic compound.

reductase

A generic term for any enzyme that catalyses a chemical reduction reaction.

re·duc·tase

(rĕ-dŭk'tās)
An enzyme that catalyzes a reduction; because all enzymes catalyze reactions in either direction, any reductase can, under the proper conditions, behave as an oxidase and vice versa; hence the term oxidoreductase.

reductase

an ENZYME that catalyses the REDUCTION of a compound.

reductase

an enzyme that catalyzes a chemical reduction.

5α-reductase
an enzyme that catalyzes the irreversible reduction of testosterone to dihydrotestosterone.
References in periodicals archive ?
Measurement of this ratio assesses for 5a-reductase enzyme activity.
Testosterone is converted to the more potent androgen, 5a-DHT, by the 5a-reductase enzyme within the prostate.
5a-Reductase enzymes may not be good targets for prostate cancer chemo-prevention, despite the biologically sound basis for their use.
Use of 5a-reductase inhibitors for prostate cancer chemoprevention: American Society of Clinical Oncology/American Urological Association 2008 Clinical Practice Guideline.
5a-Reductase Inhibition Prevents the Luteal Phase Increase in Plasma Allopregnanolone Levels and Mitigates Symptoms in Women with Premenstrual Dysphoric Disorder.
Reduced bone mass and muscle strength in male 5a-reductase type 1 inactivated mice.
5a-reductase type 2 regulates glucocorticoid action and metabolic phenotype in human hepatocytes.
In line with the known stimulating effect of increased 5a-reductase activity on cortisol clearance, a trend (P = 0.
However, the frequently reported interaction of leptin with the hypothalamus-pituitary-adrenal axis and the 5a-reductase influence on cortisol clearance remain masked if only UFF is analyzed.
Because there is little 5a-reductase activity in skeletal muscle [10], testosterone and possibly circulating DHT appear to be the key hormones for androgen action.
The enzyme 5a-reductase metabolizes testosterone to DHT in the prostate gland, liver and skin.
Finasteride is a competitive and specific inhibitor of 5a-reductase with which it slowly forms a stable enzyme complex.