DIO1

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DIO1

A gene on chromosome 1p33-p32 that encodes a thiol-requiring propylthiouracil-sensitive oxidoreductase. DIO1 activates thyroid hormone by converting the prohormone thyroxine (T4) by outer-ring deiodination to bioactive 3,3’,5-triiodothyronine (T3). It also degrades T3 and T4 by inner-ring deiodination.
References in periodicals archive ?
(5di) However, if both the divorce or separation instrument and state law fail to unambiguously provide for the termination of payments upon death, such payments may be disqualified from receiving alimony treatment.
5Di Pick-up/Navaro - now dressed to thrill and grace the drop-off point in front of the Ritz or Savoy - has come a long way.