An intermediate in purine biosynthesis.
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Table 2 Representative reactions of the "No Molecule Left Behind" principle Compound Reaction * Production Feedback pathway(s) pathway(s) Pyruvate Chorismate + [NH.sub.3] <=> TRP, rTCA Anthranilate + Pyruvate + FOLATE [H.sub.2]O Fumarate N-(L-Arginino) succinate ARG, PUR rTCA <=> Fumarate + L-Arginine 2-oxoglutarate 4-Methyl-2-oxopentanoate + LEU, VAL, rTCA L-Glutamate <=> L-Leucine ILEU, SER, + 2-Oxoglutarate LYS, HIS L-Glutamate L-Glutamine + PRPP + PUR, PYR, GLN, LEU, [H.sub.2]O <=> HIS VAL, ILEU, 5-Phosphoribosylamine + SER, LYS, Pyrophosphate + L-Glutamate HIS Glyceraldehyde L-serine + Indoleglycerol TRP RIBOSE 3-phosphate phosphate <=> L-tryptophan + Glyceraldehyde 3-phosphate + [H.sub.2]O D-Erythrose D-Fructose 6-phosphate + RIBOSE PHE, TYR.