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Synthetic analogue (antimetabolite) of thymine, in which a bromine atom takes the place of the methyl group in thymine; a mutagen.
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Initially, 5-bromouracil (0.2-0.5 g) was mixed with a solid support (alumina or celite).
Gulfishan, Genotoxic effects of 5-bromouracil on cytomorphological characters of Cichoriumintybus L., Afr.
[1] Nonstandard abbreviations: 6-TG, 6-thoguanine; 6-TGN, 6-thioguanine nucleotide; NIA, phenylmercuric acetate; 5-BU, 5-bromouracil; DTT, dithiothreitol; and HBSS, Hanks' balanced salt solution.