(redirected from 5-bromo-2-deoxy-uridine)

bro·mo·de·ox·y·ur·i·dine (BrDu),

A compound that competes with uridine for incorporation in RNA and fluoresces in ultraviolet light; used in BrDu-banding.


A thymidine analogue which induces point mutations by tautomerisation. It is incorporated into DNA during the S-phase of the cell cycle, and used to study DNA replication, DNA synthesis by flow cytometry, and cell cycle and tumour kinetics.

bromodeoxyuridine (brō´mōdēoksyur´ədēn),

n a compound that competes with uridine for incorporation in ribonucleic acid.
References in periodicals archive ?
Experiments were done in triplicate and after three days of culture, 100 [micro]l of 5-bromo-2-deoxy-uridine labeling solution was added into each well and incubation continued for 18 hrs.
Post-irradiation presence of LND significantly increased micronuclei formation, particularly in the cells that had been pre-sensitized by 5-Bromo-2-deoxy-Uridine (BrdU) (15).
Optimizing treatment of brain tumours: Effects of lonidamine and 5-bromo-2-deoxy-uridine on radiation response of human glioma cells.
Optimizing radiation therapy of brain tumours by combination of 5-bromo-2-deoxy-uridine & 2-deoxy-D-glucose.

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