(5-ARIs) are a totally different kind of drug, which shrink the glandular tissue of the prostate, reducing its bulk to eventually reduce constriction by the prostate as well.
4] The mainstay of medical treatments includes alpha-blockers, 5-alpha-reductase inhibitors
(5-ARIs), or a combination of the two.
First-line therapies indude alpha-1 adrenergic receptor antagonists (alpha-blockers) and 5-alpha-reductase inhibitors
Exclusion criteria also included: consumption of food rich in soy isoflavonoids, dietary supplements of any kind, medication with possible effects on prostate health such as antibiotics, anti-inflammatory drugs, alpha-1 -adrenoreceptor antagonist and 5-alpha-reductase inhibitors
Cancer chemopreventive approaches may include 5-alpha-reductase inhibitors
, histone deacetylase inhibitors, antioxidans, non-steroidal anti-inflammatory drugs, cholesterol-lowering statins, vitamin D analogues.
FDA-approved conventional medications used to treat BPH are of two categories, alpha-antagonists and 5-alpha-reductase inhibitors
The significant adverse effects of alpha-blockers and 5-alpha-reductase inhibitors
, which are typically prescribed for LUTS--including decreased libido and dizziness--may help account for their interest in this alternative treatmentP.
Patients were excluded if they had used 5-alpha-reductase inhibitors
, if they had undergone prior prostate surgery, had a prior diagnosis of prostate cancer, had used androgen ablative therapies, had evidence of prostatitis, or if they were allergic to fluoroquinolones.
Drugs known as 5-alpha-reductase inhibitors
like finasteride (Proscar) are widely used to treat benign prostatic hyperplasia (enlarged prostate).
Medications called 5-alpha-reductase inhibitors
(Proscar, for example) help shrink the prostate.
Previous treatment with 5-alpha-reductase inhibitors
was not allowed and alpha-blockers were discontinued at least 14 days prior to study.