5-HIAA

5-hydroxyindoleacetic acid

 [hi-drok″se-in″dōl-ah-se´tic]
a product of serotonin metabolism excreted in large amounts in patients with carcinoid tumors. Abbreviated 5-HIAA.

5-hydroxyindoleacetic acid (5-HIAA)

[hīdrok′sē·in′dōlē·əset′ik]
an acid produced by serotonin metabolism, measured in the blood and urine to aid in the diagnosis of certain kinds of tumors. It commonly rises above normal levels in whole blood in association with asthma, diarrhea, rapid heartbeat, and other symptoms and is elevated in the urine of patients with carcinoid syndrome. Its normal concentration in whole blood is 0.05 to 0.20 g/mL; its normal accumulation in urine after 24-hour collection is 1 to 5 mg.

5-HIAA

5-Hydroxy-indoleacetic acid, see there.

5-HIAA

5-hydroxyindoleacetic acid.
References in periodicals archive ?
On the other hand, the raw data on the concentration of 5-HT and 5-HIAA as well as the expression of genes and proteins, after passing normality and homogeneity of variances tests, were subjected to a two-way ANOVA to determine any significant influences of the two parameters (photoperiod and LPS-treatment), followed by Fisher's least significant difference post-hoc test.
desipramine, electroconvulsive seizures and lithium on brain-derived neurotrophic factor mRNA and protein expression in the rat brain and the correlation to 5-HT and 5-HIAA levels.
The right side of the striatal content of DA, DOPAC and 5-HIAA were determined by HPLC with an electrochemical detector (Antec, Zoeterwoude, The Netherlands).
16,17) The National Comprehensive Cancer Network (NCCN) recommends 24 hr urine 5-HIAA and chromogranin A in the diagnostic workup of suspected midgut carcinoid tumors.
The metabolites of dopamine and serotonin, DOPAC and 5-HIAA respectively, can be measured as part of the comprehensive neurotransmitter testing.
3 ng/mL; reference range, 101-283 ng/mL) and/or 24 hour urine 5-HIAA (median, 23.
Preoperative 24-hour urine for 5-HIAA was mildly elevated but postoperative repeat was normal.
2006), hallando correlaciones negativas entre los niveles de 5-HIAA en el fluido cerebroespinal y S-CON, Vista y CF+C>C.
4%), serotonin, or 24-hour urinary 5-HIAA (sensitivity 84%, specificity 88%-100%) helps in biochemical evaluation.
Se evidencia aumento de 5 kilogramos de peso acompanado de disminucion gradual de los niveles de creatinina y de 5-HIAA.
A subsequent serum chromogranin A was elevated at 52 ng/ml (reference normal <34 ng/ml) and a 24-hour urine 5-HIAA was elevated at 15 mg/24 hrs (reference range 0-6 mg/24 hrs).
No treatment-related differences in levels of CNS neurotransmitters were observed in the olfactory bulb or hypothalamus nor in levels of DA, DOPAC, HVA, 5-HT, or 5-HIAA in the midbrain, striatum, cortex, or hippocampus (data not shown).