47, XXX | definition of 47, XXX by Medical dictionary
XXX syndrome (redirected from 47, XXX)
The most common—1:1,000—chromosomal abnormality of women; most have normal IQs, but patients are often emotionally labile, and have speech and learning defects
a human sex chromosomal aberration characterized by the presence of three X chromosomes and two Barr bodies instead of the normal XX complement, so that somatic cells contain a total of 47 chromosomes; trisomy X. The condition occurs approximately once in every 1000 live female births and is confirmed diagnostically by the presence of the extra Barr body in the cells. Individuals with the anomaly show no significant clinical manifestations, although there is usually some degree of mental retardation. Because selective migration of the X chromosome occurs during meiosis, half of the offspring of a trisomy X female will be both chromosomally and phenotypically normal. Also called triple X syndrome
XXX syndrome 47, XXX The most common–1:1000 chromosomal abnormality of ♀ Clinical Clinodactyly, epicanthal folds, ocular hypertelorism, an ↑ incidence of congenital defects in Pts' children; most have normal IQs, but tend to be emotionally labile, with speech and learning defects
References in periodicals archive
In three patients 47, XXX
karyotype were found witch is consistent with literature.
Bilateral renal agenesis and Mullerian anomalies in a 47, XXX fetus.
Transition from adolescence to early adulthood: Adaptation and psychiatric status of women with 47, XXX.