S100A4

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S100A4

A gene on chromosome 1q21 that encodes a member of the S100 family of proteins, which have 2 EF-hand calcium-binding motifs. S100 proteins are localised in the cytoplasm and/or nucleus of a wide range of cells; they are involved in regulating cell cycle progression and differentiation and other intracellular activities. The S100A4-encoded protein is thought to play a role in motility, invasion and tubulin polymerisation.
 
Molecular pathology
S100A4 rearrangements have been implicated in tumour metastasis.
References in periodicals archive ?
Mikko Rantanen (16G, 42A) leads the league in scoring.
Temperatures maximales entre 30 et 35A sur les cotes et les hauteurs, et entre 36 et 42A ailleurs.
42a Devonshire Place, in Newcastle, is for sale at PS245,000, through Walton Robinson, tel: 0191 243 1000.
The counsel argued that Mr Asif's failure to disclose his or his spouse's statement of assets and liabilities under Section 42A of the Representation of Peoples Act (RoPA) 1976 entailed violation of the legal obligation and thus attracted disqualification for life.
He said that this was a mandatory requirement under Section 42A of the Representation of the People Act, 1976 and Section 25A of the Senate (Election) Act, 1975, that those parliamentarians who fail to submit yearly statements of assets and liabilities, would be suspended from respective seats of Senate or National or Provincial assemblies.
Dawn.com Islamabad The Election Commission of Pakistan (ECP) on Monday suspended the membership of 261 lawmakers for failure to submit details of their finances under sub-section 42A of the Representation of People Act (RoPA) by Sept 30.
Montenegrin meteorologists also reported temperatures of up to 42A;C.
SUBMITTED | |Gary Oldroyd, outline application for one property, 42A, Station Road, Fenay Bridge.
The models CA, 42A and 43A are general purpose, single-axis accelerometers.
Le ciel sera degage durant les prochains jours et le mercure grimpera progressivement a partir de jeudi pour atteindre les 40A vendredi et samedi, a appris, hier, l'APS aupres de la cellule de communication de l'ONM.Dans les regions interieures du pays, les temperatures varieront entre 35A et 40A et pourraient enregistrer vendredi un pic de 42A a Relizane, Mascara, Guelma et Souk Ahras.
Miss Montgomery said Marks, of no fixed abode, and Golding, of Cross Farm Road, Harborne, 'routinely travelled to Worcester' on the train from Birmingham New Street and Moor Street stations to sell drugs from a property at 42a Teme Road.