3-oxothiolase | definition of 3-oxothiolase by Medical dictionary
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thiolase
(redirected from
3-oxothiolase
)
a·ce·tyl-CoA a·ce·tyl·trans·fer·ase
an acetyltransferase forming acetoacetyl-CoA from two molecules of acetyl-CoA, releasing one CoA. A key step in ketogenesis and sterol synthesis.
Synonym(s):
acetoacetyl-CoA thiolase
,
acetyl-CoA thiolase
,
thiolase
thiolase
An obsolete generic term for any enzyme (e.g., acetyl CoA acetyltransferase [EC 2.3.1.9]) which catalyses a reaction between a compound, R–R’, and a thiol, R’–SH, forming R–S–R’ and R'–H.
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2-methylacetoacetyl-CoA thiolase
acetyl-CoA acetyltransferase
acetyl-CoA acyltransferase
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newborn screening
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