3-mercaptopyruvate sulfurtransferase

3-·mer·cap·to·py·ru·vate sul·fur·trans·fer·ase

an enzyme that is a part of the cysteine catabolic pathway; it catalyzes the conversion of 3-mercaptopyruvate to pyruvate and H2S; a deficiency of this enzyme will result in elevated urine concentrations of 3-mercaptopyruvate as well as of 3-mercaptolactate, both in the form of disulfides with cysteine.
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2]S) is an endogenous gaseous signaling molecule in mammalian tissues, which is enzymatically synthesized by cystathionine [beta]-synthase (CBS), cystathionine y-lyase (CSE), and 3-mercaptopyruvate sulfurtransferase (3-MST) [17-19].
To this end, we found that cells expressing 3-mercaptopyruvate sulfurtransferase (3MST) and cysteine aminotransferase (CAT) contain increased levels of bound sulfane sulfur.
2011) Thioredoxin and dihydrolipoic acid are required for 3-mercaptopyruvate sulfurtransferase to produce hydrogen sulfide.
2]S in the human body is catalyzed by several enzymes, including two pyridoxal-5'-phosphate- (PLP-) dependent enzymes, namely, cystathionine-[beta]-synthase (CBS) and cystathionine-[gamma]-lyase (CSE), and 3-mercaptopyruvate sulfurtransferase (MST) [4].
Other enzymes such as 3-mercaptopyruvate sulfurtransferase (MST) and cysteine aminotransferase (CAT) are also important in specific tissue types [12].
2]S-generating enzymes cystathionine-[beta]-synthase (CBS), cystathionine-[gamma]-lyase (CSE), and 3-mercaptopyruvate sulfurtransferase (3MST) and metabolize cysteine [15].
Recently, 3-mercaptopyruvate sulfurtransferase (3-MST) was reported as the third enzyme for [H.
2]S-producing enzyme, 3-mercaptopyruvate sulfurtransferase (3-MST), has recently been discovered; this enzyme generates [H.
Recently, it was found that another mitochondrial enzyme, 3-mercaptopyruvate sulfurtransferase (3-MST) in conjunction with cysteine aminotransferase (CAT), contributes significantly in generating [H.
2]S-producing pathway, which is governed by 3-mercaptopyruvate sulfurtransferase (3-MST), complements and balances the bioenergetic activity of Krebs cycle-derived electron donors in the Hepa1c1c7 cell line [18].
2]S, including cystathionine [gamma]-lyase (CSE), cystathionine [beta]-synthase (CBS), and 3-mercaptopyruvate sulfurtransferase (3MST) [51].
3) and then 3-mercaptopyruvate is desulfurated by 3-mercaptopyruvate sulfurtransferase (MST; EC 2.